| Name | Type | Class | Effects |
|---|---|---|---|
 Soulfeast Tine | Legendary Spear | Requirements +-20% 7% Life stolen per hit 7% Mana stolen per hit 20% Slower Stamina Drain +150-190% Enhanced Damage +150-250 to Attack Rating | |
 Soul Harvest | Legendary Polearm | 30% Chance of Open Wounds +45 to Attack Rating All Resistances +20 +50-90% Enhanced Damage 10% Mana stolen per hit +5 to Energy | |
 Soul Drainer | Legendary Gloves | +90% Enhanced Defense 4-7% Mana stolen per hit 4-7% Life stolen per hit -50 to Monster Defense Per Hit | |
 Snowclash | Legendary Belt | 5% Chance to cast level 0 Blizzard when struck +15 Cold Absorb +15% to Maximum Cold Resist +13-21 to Minimum Cold Damage +130% Enhanced Defense +2 to Blizzard (Sorceress Only) +3 to Glacial Spike (Sorceress Only) +2 to Chilling Armor (Sorceress Only) | |
 Snakecord | Legendary Belt | +40 to Minimum Poison Damage Poison Resist +25% +10 Defense +20% Enhanced Defense Replenish Life +5 Poison Length Reduced by 50% | |
|
| Legendary Runeword | +250 Defense vs. Missile +75% Enhanced Defense All Resistances +50 +20% Faster Hit Recovery +-1 to Light Radius Level 6 Weaken (18/18 Charges) Knockback +10 to Energy | |
 Skystrike | Legendary Bow | +1-250 to Minimum Lightning Damage +100 to Attack Rating +10 to Energy +30% Increased Attack Speed +150-200% Enhanced Damage 2% Chance to cast level 6 Meteor on striking +1 to Amazon Skill Levels | |
 Skullder's Ire | Legendary Armor | +1 to All Skills 123.75% Better Chance of Getting Magic Items (Based on Character Level) +160% Enhanced Defense Magic Damage Reduced by 10 Repairs 20 durability per second | |
 Skull Splitter | Legendary Axe | Hit Blinds Target Regenerate Mana 20% +1 to Minimum Lightning Damage +12-15 to Maximum Lightning Damage +50-100 to Attack Rating +60-100% Enhanced Damage 15% Chance of Open Wounds | |
 Skull Collector | Legendary Staff | Increase Maximum Mana 20% +20 to Mana after each Kill +2 to All Skills 99% Better Chance of Getting Magic Items (Based on Character Level) | |
 Skin of the Vipermagi | Legendary Armor | +120% Enhanced Defense All Resistances +20-35 +30% Faster Cast Rate Magic Damage Reduced by 9-13 +1 to All Skills | |
 Skin of the Flayed One | Legendary Armor | Repairs 10 durability per second Replenish Life +15-25 5-7% Life stolen per hit +150% Enhanced Defense Attacker Takes Damage of 15 | |
 Skewer of Krintiz | Legendary Sword | Ignore Target's Defense +10 to Strength +10 to Dexterity 7% Mana stolen per hit +50% Enhanced Damage +3-7 to Minimum Damage | |
 Silkweave | Legendary Boots | +150% Enhanced Defense +5 to Mana after each Kill +200 Defense vs. Missile Increase Maximum Mana 10% +30% Faster Run/Walk | |
 Silks of the Victor | Legendary Armor | 5% Mana stolen per hit +1 to All Skills +2 to Light Radius +100% Enhanced Defense | |
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| Legendary Runeword | 4% Mana stolen per hit Hit Blinds Target +200% Enhanced Damage +20% Increased Attack Speed All Resistances +75 +2 to All Skills +20% Faster Hit Recovery Hit Causes Monster to Flee 32% +50 to Attack Rating against Undead +75% Damage to Undead Requirements +-20% 30% Better Chance of Getting Magic Items +2 to Mana after each Kill 7% Mana stolen per hit | |
 Sigon's Wrap | Set Belt | +198 Defense (Based on Character Level) (2 Items) 10% Life stolen per hit +100 Defense Fire Resist +12% Attacker Takes Damage of 12 Damage Reduced by 7 +24 to Maximum Fire Damage +20 to Mana Fire Resist +20% +20 to Life | |
 Sigon's Visor | Set Helm | +792 to Attack Rating (Based on Character Level) (2 Items) 10% Life stolen per hit +100 Defense Fire Resist +12% Attacker Takes Damage of 12 Damage Reduced by 7 +24 to Maximum Fire Damage +20 to Mana +30 to Mana +25 Defense | |
 Sigon's Shelter | Set Armor | Attacker Takes Damage of 20 (2 Items) 10% Life stolen per hit +100 Defense Fire Resist +12% Attacker Takes Damage of 12 Damage Reduced by 7 +24 to Maximum Fire Damage +20 to Mana +25% Enhanced Defense Lightning Resist +30% | |
 Sigon's Sabot | Set Boots | +50 to Attack Rating (2 Items) 50% Better Chance of Getting Magic Items (3 Items) 10% Life stolen per hit +100 Defense Fire Resist +12% Attacker Takes Damage of 12 Damage Reduced by 7 +24 to Maximum Fire Damage +20 to Mana +20% Faster Run/Walk Cold Resist +40% | |
 Sigon's Guard | Set Shield | 10% Life stolen per hit +100 Defense Fire Resist +12% Attacker Takes Damage of 12 Damage Reduced by 7 +24 to Maximum Fire Damage +20 to Mana +1 to All Skills 20% Increased Chance of Blocking | |
 Sigon's Gage | Set Gloves | +30% Increased Attack Speed (2 Items) 10% Life stolen per hit +100 Defense Fire Resist +12% Attacker Takes Damage of 12 Damage Reduced by 7 +24 to Maximum Fire Damage +20 to Mana +10 to Strength +20 to Attack Rating | |
 Shaftstop | Legendary Armor | +250 Defense vs. Missile Damage Reduced by 30% +60 to Life +180% Enhanced Defense | |
 Shadowfang | Legendary Sword | 9% Mana stolen per hit Cold Resist +20% +-2 to Light Radius +10-30 to Minimum Cold Damage +100% Enhanced Damage 9% Life stolen per hit | |
 Shadow Killer | Legendary Hand to Hand 2 | +170-220% Enhanced Damage -25% Target Defense Freezes target +10-15 to Mana after each Kill Indestructible |