There is no real point before lvl 60 and the Nephalem Valor buff. That being said I can definately see the difference between having 5 stacks of the buff and not having it at all. Quest bosses like Skeleton King, Cydea, Belial, Diablo etc. all seem to drop 4+ blues and 2+ rares. But it's not just that, normal mobs and even barrels, dead bodies etc. are definately dropping better items.
Thats just my experience so far atm doing act I Inferno.
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Thats just my experience so far atm doing act I Inferno.